As an orchestral musician, Lisa Wolynec is a principal of the critically acclaimed Gateway Chamber Orchestra, with whom she premiered Lee Hoiby's Flute Concerto, and principal of the Paducah Symphony. She has also performed with the Baton Rouge Symphony, Knoxville Symphony, Owensboro Symphony,  the Nashville Opera, and has been a guest soloist with the Gateway Chamber Orchestra, the Dallas Chamber Orchestra and the Paducah Symphony. She has been a winner in various competitions including the Texas Flute Society Concerto Competition, the National Flute Association Orchestral Competition, the NFA Convention Performers Competition and she was a semi-finalist in the NFA Young Artist Competition.

As Professor of Flute at Austin Peay State University, she has built and maintained a vibrant studio with students going on to prominent graduate programs and excellent teaching positions. She has hosted residencies by flutists such as William Bennett, Lorna McGhee, and Rhonda Larson and is the Director of the William Bennett Summer Flute Academy. As a member of the Mid-South Flute Society, she has served on the Board of Directors, as Competition Coordinator, Program Chair, and President.